Effects of orthotopic liver and fetal liver transplantation in hereditary hyperbilirubinemic Gunn rat

[Orthotopic liver transplantation in polycystic liver disease].

INTRODUCTION There is currently no effective medical therapy for polycystic liver (PCL). Cyst puncture and sclerotherapy, cyst fenestration, or partial hepatic resections have been used as palliative treatments. Orthotopic liver transplantation (OLT) has become the treatment of choice for terminal PCL, being indicated in patients with limiting symptoms not susceptible to any other medical treat...

Orthotopic Liver Transplantation

Orthotopic Liver Transplantation

A 7-year-old girl with progressive ataxia, spasticity, supranuclear ophthalmoplegia, and sea-blue histiocytes in her bone marrow underwent orthotopic liver transplantation for hepatocellular carcinoma. After an initial period of stabilization, she has shown progression of neurologic symptoms with recurrence of storage material in the transplanted liver. Pediatrics 1986;77:104-106; lipidosis, se...

Aprotinin in orthotopic liver transplantation.

Aprotinin is a protease inhibitor isolated from bovine lungs and othcr lissues. Its biochcmical struc!Urc, a single-chain polypeptide of 6.5 12 kD , and biophysical properties are weH defined. I The activity of commcrcial preparations of apralini n is usually describcd in kallikrein inac ti valor unils (KIU) , 0. 1 million KIU being equivalent 102. 15 j-Lmol of apralinin per liter. Sy inhibitin...

Orthotopic Liver Transplantation in Rats

Clinical progress in the field of liver transplantation has been largely supported by animal models(1,2). Since the publication of the first orthotopic rat liver transplantation in 1979 by Kamada et al.(3), this model has remained the gold standard despite various proposed alternative techniques(4). Nevertheless, its broader use is limited by its steep learning curve(5). In this video paper,...